Wednesday, October 11, 2017

The effects of Psychedelics, Growth

For the personal psych I do see the benefits of Psychedelic therapy
to get over the problems that people might have!
In all therapy there is the point to realize there is a problem and
to give the reins to the therapist.

The point is to understand there is a problem and to say please help!
Help? In life lovers, love and heal but in the setting of hell Psychedelic therapy
is the resolve!

~~~~~Psycholytic therapy involves the use of low to medium doses of psychedelic drugs, repeatedly at intervals of 1–2 weeks. The therapist is present during the peak of the experience and at other times as required, to assist the patient in processing material that arises and to offer support when necessary. This general form of therapy was utilized mainly to treat patients with neurotic and psychosomatic disorders. The name, coined by Ronald A. Sandison, literally meaning "soul-dissolving", refers to the belief that the therapy can dissolve conflicts in the mind. Psycholytic therapy was historically an important approach to psychedelic psychotherapy in Europe, but it was also practiced in the United States by some psychotherapists including Betty Eisner.

An advantage of psychedelic drugs in exploring the unconscious is that a conscious sliver of the adult ego usually remains alert during the experience. Throughout the session, patients remain intellectually alert and remember their experiences vividly. In this highly introspective state, they also are actively cognizant of ego defenses such as projection, denial, and displacement as they react to themselves and their choices in the act of creating them.

The ultimate goal of the therapy is to provide a safe, mutually compassionate context through which the profound and intense reliving of memories can be filtered through the principles of genuine psychotherapy. Aided by the deeply introspective state attained by the patient, the therapist assists him/her in developing a new life framework or personal philosophy that recognizes individual responsibility for change.

It's about healing... To have growth and yes Psychedelics do make us grow.
It helps to repair the brain or jump starts the brain in a early age in a therapist
supervised session. Give a homeless person slipped me LSD when I was a kid
I acknowledge that it helped me in my multiple intelligences that set
my thinking in a multiple format. Or brought me questions and set me on a path
as I wondered what the hell that was. Either way Growth!

~~~~~Psychedelic mushrooms already have a reputation for helping people open their minds and broaden their perspective on the world. They have shown an ability to combat mental disorders like depression and anxiety. Now, research is showing that the magic mushrooms can actually help physically rebuild a damaged brain.

In a study conducted by the University of South Florida and published in 2013 in the Experimental Brain Research journal, researchers measured the effects of mushrooms on mice that had been conditioned to fear certain stimuli.

The results were striking: Not only could psilocybin, the main active ingredient in psychedelic mushrooms, help them get over their fear, it promoted cell growth and regeneration in their brains.

During the experiment, mice were exposed to an auditory tone while receiving an electric shock, training them to fear the noise even when the shock was not administered.

Mice that received low doses of psilocybin, however, were quickly able to shed their aversion to the tone, while mice that did not take the substance took longer to return to normal. “They stopped freezing; they lost their fear,” study co-author Dr. Juan Sanchez-Ramos said to Live Science.

What’s more, the psychedelic mice showed growth in new brain cells, perhaps erasing memories of the fear response. Researchers think that the psilocybin is binding to brain receptors that stimulate growth and healing, acting on the hippocampus, a small part of the brain that is essential to learning and forming memories. Since PTSD is thought to result from a similar response in which patients cannot separate a stimulus from a traumatic event, psilocybin could perhaps help them heal their brains just like it did for the mice.

“Memory, learning, and the ability to relearn that a once threatening stimuli is no longer a danger absolutely depends on the ability of the brain to alter its connections,” study leader Dr. Briony Catlow of the Lieber Institute for Brain Development said to Real Clear Science. “We believe that neuroplasticity plays a critical role in psilocybin accelerating fear extinction.”

“It is highly possible that in the future we will continue these studies since many interesting questions have come up from these experiments,” Catlow said. “The hope is that we can extend the findings to humans in clinical trials.”

Psychedelics work, in part, by overriding the “default mode network” in the brain, which is thought to be responsible for wandering minds, self-criticism and an inability to focus on the outside world. Instead, the substances help people focus on living in the moment, similar to many Eastern meditation practices. That can also help with PTSD as well as other mental disorders like depression.

“People with depression have overactive default mode networks and so ruminate on themselves, on their inadequacies, on their badness, that they are worthless, that they have failed — to an extent that is sometimes delusional,” David Nutt, of the Imperial College London’s Neuropsychopharmacology Unit, said to Natural News. “[P]silocybin appears to block that activity and stops this obsessive rumination.”

The therapeutic value seems clear. “[Psilocybin] facilitates extinction of the classically conditioned fear response, and this, and similar agents, should be explored as potential treatments for post-traumatic stress disorder and related conditions,” the study concludes. However, despite its demonstrated success and unlimited potential, psilocybin is currently banned by the U.S. government, considered a drug of abuse with no medical value.

~~~~~Researchers in Brazil have used miniature human brains to reveal the effects of psychedelics on neural plasticity, inflammation and neurodegeneration. They shared the results of their experiments this week in the journal Scientific Reports.

"For the first time we could describe psychedelic related changes in the molecular functioning of human neural tissue," lead study author Stevens Rehen, a professor at the Federal University of Rio de Janeiro, said in a news release.

To study the impact of psychedelics on the brain, scientists exposed cerebral organoids -- cultures of neural cells that approximate a developing brain -- to dimethyltryptamine, or 5-MeO-DMT, a psychedelic compound. Mass spectrometry-based proteomics, a novel imaging technique, allowed researchers to analyze the compound's effects on thousands of neural proteins.

The analysis revealed an increase in the production of proteins related to synaptic formation and maintenance, as well as proteins linked with the regulation of learning and memory. The compound also decreased the production of proteins linked with inflammation, degeneration and brain lesions.

"Results suggest that classic psychedelics are powerful inducers of neuroplasticity, a tool of psychobiological transformation that we know very little about," said co-author Sidarta Ribeiro, director of the Brain Institute at the Federal University of Rio Grande do Norte.

Previous studies have suggested psychedelic drugs, including LSD and MDMA, have anti-inflammatory and antidepressant qualities, but until now, scientists have struggled to identify the molecular pathways through which the substances deliver their therapeutic effects.

"Our study reinforces the hidden clinical potential of substances that are under legal restrictions, but which deserve attention of medical and scientific communities," Rehen said.